Genetics 466 Course Outline - Fall 2004
2:25 MWF 125 Biochemistry
Date
Lecture Topic
Readings
Suggested Problems
Part 1.
Genes, Chromosomes and Linkage
Sept 3
1. Mendel and The Study of Inheritance
1:3-20; 3:52-58
3: Q1, 2, 4-10
Sept 8
2. Probability for Genetic Events
3:59-61
3: Q17, 22, 23
Sept 10
3. Probability for Repeated Trials
3:64-69
3: Q15-16, 18-21, 27
Sept 13
4. Testing Genetic Hypotheses
3:61-63
3: Q3, 11-14
Sept 15
5. Extensions to Mendelism
4:72-87
4: Q2, 3, 6, 7-12, 19-20.
Sept 17
6. The Inheritance of Complex Traits
5: 90-98
5: Q1, 3-8
Sept 20
7. Nature versus Nurture
5: 98-105
5: Q9, 10, 11, 13-19
Sept 22
8. Genetics of Plant and Animal Breeding
-
-
Sept 24
9. Cell Cycle, Mitosis and Meiosis
2:22-48
2: Q1-4, 9, 10, 12, 19, 21, 22, 24
Sept 27
10. Chromosomes, Sex and Mendel
6:114-132
6: Q2-11, 14-21, 24.
Sept 29
11. Chromosome Number
7:134-148
7: Q1, 3-8, 11, 12
Oct 1
12. Chromosome Rearrangements
7:148-153, 169-170
7: Q14-16, 18, 22-26
Oct 4
13. Linkage and Mapping I
8:156-174
8: Q1, 3, 6, 7-17
Oct. 6
14. Linkage and Mapping II
9:178-196
8: Q18-19, 21-26, 29-32
Oct. 8
15. Linkage and Mapping III
Hand-out
9: Q1,4-7, 9-12, 16-18, 22-23
Part 2.
Molecular Biology of the Gene
Oct. 11
16 Central Dogma I: DNA
10: 204-215
10:BX 1-4, TYK 1,2 ; Q: 1, 5, 7, 8, 10-15
Oct 12 Exam I Tuesday Evening 7:15 till 9:15 – Room to be announced
Oct. 13
17. Central Dogma II: Replication
11: 237-260
11: BX 1, 3-5, TYK 1; Q: 1-6, 10, 12
Oct. 15
18. Central Dogma III: RNA and Transcription
12: 273-285
12: BX 1, 2; Q: 1- 4, 7 (1st part)
Oct. 18
19. Translation and the Genetic Code I
13: 303-307
13: 321-327
13: BX 1, 2, 4, 5, TYK none;
Q:1, 8-10, 14-16, 18, 22
Oct. 20
20. Translation and the Genetic Code II
13: 308-320
13: BX 3, TYK 1,2; Q: 2, 5-7, 19, 23-25, 29, 30, 32, 33
Oct. 22
21. Gene Expression I: lac operon
23: 573-582
23: BX 1-3, TYK 1; Q: 1, 3-9
Oct. 25
22. Gene Expression II: operators and repressors
23: 583-587
23: BX 4; Q: 11, 13, 15, 18
Oct. 27
23. Gene Expression III: phage life cycle
23: 588-594
23: Bx 5, TYK 2; Q: 23-28, 30
Oct 29
24. Eukaryote Gene Structure and Expression
12: 285-290
24: 600-608
12: BX 3, TYK 1, 2; Q: 5-8, 14, 24, 29, 32
24: BX 1; Q: 1, 6
Nov 1
25. Yeast Mating Type
Handout on Mating Type
Problem Set # 4
Nov 3
26. Yeast Mating Type
Handout on Mating Type
Problem Set # 4
Nov 5
27. Animal Development
25: 629-635
Problem Set # 5
Nov 8
28. Sean Animal Development II
25: 640-649
25: BX 3 and Problem Set # 5
Part 3.
Population and Evolutionary Genetics
Nov 10
29. Life and Times of Charles Darwin
None
Think and reflect
Nov 11 Exam II Thursday Evening 7:15 till 9:15 – Room to be announced
Nov 12
30. Animal Evolution
1-13 (Packet)
None
Nov 15
31. Building Complex Animals I
25: 647-651
25: BX 4 & Problem Set # 6, Q23, 24, 25
Nov 17
32. Building Complex Animals II
55-69 (Packet)
Problem Set # 6
Nov 19
33. Evolution of the Toolkit I
73-83 (Packet)
Problem Set # 6
Nov 22
34. Evolution of the Toolkit II
103-127 (Packet)
Problem Set # 7
Nov 24
35. Diversification of Body Plans and Body Parts I
131-148 (Packet)
Problem Set # 7
Nov 29
36. Diversification of Body Plans and Body Parts II
148-156 (Packet)
Problem Set # 7
Dec 1
37. Model Organisms
28: 695-713
28: BX2, 3; TYK; Q1, 3, 8, 10, 11, 18, 21
Dec 3
38. Genome Evolution
21: 527-536, 540-543
21: Q21, 22
Dec 6
39. Hardy-Weinberg & The Gene Pool Concept
29:719-727
29: Q1-12
Dec 8
40. Inbreeding
5:105-111
5: Q20-23
Dec 9 Exam III Thursday Evening 7:15 till 9:15 – Room to be announced
Dec 10 41. Genetic Drift 29:730
732, 733 29: Q24, 25, 26
Dec 13 42. Natural Selection 29: 727
730, 732
737 29: Q19, 20, 21, 22, 29, 30
Dec 15 43. Review or Summary
Dec 19 Final Exam - covers the whole course (Monday 12/20, 10:05 AM - Room to be announced)