Laboratory of Molecular Biology

Loci is a Biophotonics instrumentation laboratory stemming from the Research activities of Kevin Eliceiri, Patti Keely, John White and other LOCI investigators.

The mission of LOCI is to develop advanced optical and computational techniques for imaging and experimentally manipulating living specimens.

New and improved imaging instrumentation and optical-based experimental techniques are being developed.

These projects are driven by demands arising from the scientific studies of external collaborators and the principal investigators and opportunities that arise with the emergence of new technology. Instrumentation development is undertaken in a form that is both accessible and beneficial to the scientific community.

FACULTY

Kurt Amann and the Amann lab group
Molecular-level analysis of the actin cytoskeleton and its role in cell structure and motility

Deric Bownds (emeritus)

Sean Carroll and the Carroll lab group
Gaining a comprehensive understanding of the genetic control of body pattern in fruit flies, butterflies, and other animals

Michael Culbertson
Mechanisms of synthesis, decay, and function of RNA using the yeast Saccharomyces cerevisiae as a model system

Patricia Keely
Integrin and small GTPase signaling events in differentiation and transformation

Judith Kimble
Regulation of development in the nematode Caenorhabditis elegans

Ching Kung and the Kung lab group
Sensory transductions in microbes

John White (chair) and the White lab group
Cell cleavage in developing metazoans (Caenorhabditis elegans) and cell fates

AFFILIATE FACULTY

William Bement
Cytoskeleton control of cell division, wound healing, and endocytosis

ACADEMIC STAFF INVESTIGATORS

Kevin Eliceiri
Director LOCI

Yoshiro Saimi
Honorary Research Professor, Kung Lab

COLLABORATORS

Brenda Ogle, Engr/Biomedical Engineering
Justin Williams, Engr/Biomedical Engineering